Question 1

An appropriately increased RPI greater than 3 is associated with:

Accepted Answer

A)   Iron deficiency anemia
B)   Macrocytic megaloblastic anemia
C)   Hemolytic anemia
D)   Sideroblastic anemiaE) A) and D)
F) A) and C)

Question 2

All of the following are physiologic adaptations the body makes when a slow drop in the number of red cells occurs except:

Accepted Answer

A)   Erythropoietin level increases.
B)   Oxygen dissociation curve shifts to left.
C)   Cardiac output increases.
D)   Respiratory rate increases.E) C) and D)
F) A) and C)

Question 3

Which of the following is an example of a morphologic classification of anemia?

Accepted Answer

A)   Normocytic normochromic
B)   Loss of blood
C)   Increased destruction
D)   Impaired productionE) B) and D)
F) B) and C)

Question 4

What percentage of red cells is destroyed and replaced daily in a normal adult?

Accepted Answer

A)   1%
B)   5%
C)   10%
D)   20%E) All of the above
F) A) and B) A

Question 5

Compare results of various tests in effective versus ineffective erythropoiesis.

Accepted Answer

A)   Both have increased rate of erythropoiesis in the bone marrow.
B)   Both have an elevated reticulocyte production index (RPI)  greater than 3.
C)   Both have normal release of RBCs from the bone marrow.
D)   Both have significantly shortened red cell survival in circulation.E) C) and D)
F) A) and B)

Question 6

The red cell histogram is wider than normal. Which of the following is true?

Accepted Answer

A)   The red blood cell distribution width (RDW)  is decreased.
B)   Most cells are larger than normal.
C)   The coefficient of variation was calculated incorrectly.
D)   Anisocytosis is present.E) B) and D)
F) A) and B)

Question 7

The anemia found in liver disease is:

Accepted Answer

A)   Macrocytic nonmegaloblastic
B)   Microcytic hypochromic
C)   Macrocytic megaloblastic
D)   Microcytic normochromicE) A) and C)
F) A) and B)

Question 8

Two different patients both have hemoglobins in the 5.0 to 6.0 g/dL range. One has pallor, fatigue, and headaches, whereas the other is experiencing life-threatening shock. Which of the following is probably the major difference between the two patients?

Accepted Answer

A)   The morphologic classification of the anemia
B)   Whether other cell lines (platelets or white cells)  are also involved
C)   The patient's sex
D)   How quickly the anemia developedE) A) and B)
F) B) and C)

Question 9

Match the letter of the correct composition for the inclusion with the number for the inclusion.
Correct identification of inclusions in RBCs, when present, provides useful clinical information. They often help suggest the possible cause of an anemia, and thus further appropriate testing. The first list provides some red cell inclusions. The second list provides choices for composition.

-Howell-Jolly body

Accepted Answer

A)  Ferric nonheme iron
B)  Deoxyribonucleic acid (DN
A)  
C)  Precipitated ribonucleic acid (RN
A)  
D)  Denatured hemoglobinE) C) and D)
F) B) and D)

Question 10

What test is used along with the mean cell volume (MCV)  to morphologically classify anemias?

Accepted Answer

A)   Red blood count
B)   Hemoglobin
C)   Hematocrit
D)   RDWE) A) and C)
F) All of the above D

Question 11

Which shape of red cell is described as a round, dense cell with no area of central pallor?

Accepted Answer

A)   Sickle cell
B)   Target cell
C)   Burr cell
D)   SpherocyteE) A) and B)
F) C) and D)

Question 12

Which of the following red blood cell (RBC)  findings are specific for a certain condition as opposed to being nonspecific and found in many conditions?

Accepted Answer

A)   Ovalocytes
B)   Poikilocytosis
C)   Sickle cells
D)   Burr cellsE) C) and D)
F) All of the above

Question 13

Which of the following is true of ineffective erythropoiesis?

Accepted Answer

A)   Lymphopenia and anemia are present.
B)   RBC production in bone marrow is increased.
C)   Release of RBCs to the peripheral blood is normal.
D)   RBC survival in circulation is less than 40 days.E) A) and D)
F) B) and D)

Question 14

Which of the following is typically a macrocytic anemia?

Accepted Answer

A)   Thalassemia
B)   Iron deficiency
C)   Folate deficiency
D)   AplasticE) A) and C)
F) None of the above C

Question 15

Which of the following conditions would warrant a bone marrow aspiration?

Accepted Answer

A)   Iron deficiency in a patient with colon cancer
B)   Severe hereditary spherocytosis
C)   Disseminated intravascular coagulation (DI
C)   with very low hemoglobin and marked red cell fragments
D)   Not possible to determine obvious reason for anemiaE) A) and D)
F) A) and C)

Question 16

What is the best definition of anemia?

Accepted Answer

A)   Red cell count 10% lower than the patient's baseline
B)   Decreased hemoglobin, hematocrit, and red cell count compared with healthy people in the same demographic group
C)   Hemoglobin below 12 g/dL
D)   Any clinical condition resulting in shortness of breath, increased heart rate, pallor, and fatigueE) B) and C)
F) B) and D)

Question 17

Match the letter of the correct composition for the inclusion with the number for the inclusion.
Correct identification of inclusions in RBCs, when present, provides useful clinical information. They often help suggest the possible cause of an anemia, and thus further appropriate testing. The first list provides some red cell inclusions. The second list provides choices for composition.

-Heinz body

Accepted Answer

A)  Ferric nonheme iron
B)  Deoxyribonucleic acid (DN
A)  
C)  Precipitated ribonucleic acid (RN
A)  
D)  Denatured hemoglobinE) A) and D)
F) A) and C)

Question 18

Describe the morphologic appearance of the red cells given the following results. RBC: 1.89*1012/L
Hemoglobin: 7.5 g/dL
Hematocrit: 21.0%
RDW: 18.5

Accepted Answer

A)   Macrocytic with anisocytosis
B)   Normocytic normochromic with anisocytosis
C)   Microcytic hypochromic with little anisocytosis
D)   Macrocytic with most cells the same sizeE) A) and B)
F) All of the above

Question 19

Match the letter of the correct composition for the inclusion with the number for the inclusion.
Correct identification of inclusions in RBCs, when present, provides useful clinical information. They often help suggest the possible cause of an anemia, and thus further appropriate testing. The first list provides some red cell inclusions. The second list provides choices for composition.

-Basophilic stippling

Accepted Answer

A)  Ferric nonheme iron
B)  Deoxyribonucleic acid (DN
A)  
C)  Precipitated ribonucleic acid (RN
A)  
D)  Denatured hemoglobinE) None of the above
F) C) and D)

Question 20

What is the approximate average life span of a normal RBC in circulation?

Accepted Answer

A)   10 Days
B)   20 Days
C)   80 Days
D)   120 DaysE) B) and D)
F) A) and B)

Exam 18: Anemias: Red Blood Cell Morphology and Approach to Diagnosis

An appropriately increased RPI greater than 3 is associated with:

Correct Answer
verified

All of the following are physiologic adaptations the body makes when a slow drop in the number of red cells occurs except:

Correct Answer
verified

Which of the following is an example of a morphologic classification of anemia?

Correct Answer
verified

What percentage of red cells is destroyed and replaced daily in a normal adult?

Correct Answer
verified
A

Compare results of various tests in effective versus ineffective erythropoiesis.

Correct Answer
verified

The red cell histogram is wider than normal. Which of the following is true?

Correct Answer
verified

The anemia found in liver disease is:

Correct Answer
verified

Two different patients both have hemoglobins in the 5.0 to 6.0 g/dL range. One has pallor, fatigue, and headaches, whereas the other is experiencing life-threatening shock. Which of the following is probably the major difference between the two patients?

Correct Answer
verified

Correct Answer
verified

What test is used along with the mean cell volume (MCV) to morphologically classify anemias?

Correct Answer
verified
D

Which shape of red cell is described as a round, dense cell with no area of central pallor?

Correct Answer
verified

Which of the following red blood cell (RBC) findings are specific for a certain condition as opposed to being nonspecific and found in many conditions?

Correct Answer
verified

Which of the following is true of ineffective erythropoiesis?

Correct Answer
verified

Which of the following is typically a macrocytic anemia?

Correct Answer
verified
C

Which of the following conditions would warrant a bone marrow aspiration?

Correct Answer
verified

What is the best definition of anemia?

Correct Answer
verified

Correct Answer
verified

Describe the morphologic appearance of the red cells given the following results. RBC: 1.89*10¹²/L Hemoglobin: 7.5 g/dL Hematocrit: 21.0% RDW: 18.5

Correct Answer
verified

Correct Answer
verified

What is the approximate average life span of a normal RBC in circulation?

Correct Answer
verified

Exam 18: Anemias: Red Blood Cell Morphology and Approach to Diagnosis

An appropriately increased RPI greater than 3 is associated with:

Correct AnswerverifiedShow Answer

All of the following are physiologic adaptations the body makes when a slow drop in the number of red cells occurs except:

Correct AnswerverifiedShow Answer

Which of the following is an example of a morphologic classification of anemia?

Correct AnswerverifiedShow Answer

What percentage of red cells is destroyed and replaced daily in a normal adult?

Correct AnswerverifiedA

Compare results of various tests in effective versus ineffective erythropoiesis.

Correct AnswerverifiedShow Answer

The red cell histogram is wider than normal. Which of the following is true?

Correct AnswerverifiedShow Answer

The anemia found in liver disease is:

Correct AnswerverifiedShow Answer

Two different patients both have hemoglobins in the 5.0 to 6.0 g/dL range. One has pallor, fatigue, and headaches, whereas the other is experiencing life-threatening shock. Which of the following is probably the major difference between the two patients?

Correct AnswerverifiedShow Answer

Correct AnswerverifiedShow Answer

What test is used along with the mean cell volume (MCV) to morphologically classify anemias?

Correct AnswerverifiedD

Which shape of red cell is described as a round, dense cell with no area of central pallor?

Correct AnswerverifiedShow Answer

Which of the following red blood cell (RBC) findings are specific for a certain condition as opposed to being nonspecific and found in many conditions?

Correct AnswerverifiedShow Answer

Which of the following is true of ineffective erythropoiesis?

Correct AnswerverifiedShow Answer

Which of the following is typically a macrocytic anemia?

Correct AnswerverifiedC

Which of the following conditions would warrant a bone marrow aspiration?

Correct AnswerverifiedShow Answer

What is the best definition of anemia?

Correct AnswerverifiedShow Answer

Correct AnswerverifiedShow Answer

Describe the morphologic appearance of the red cells given the following results. RBC: 1.89*1012/L Hemoglobin: 7.5 g/dL Hematocrit: 21.0% RDW: 18.5

Correct AnswerverifiedShow Answer

Correct AnswerverifiedShow Answer

What is the approximate average life span of a normal RBC in circulation?

Correct AnswerverifiedShow Answer

Correct Answer
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Correct Answer
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Correct Answer
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Correct Answer
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A

Correct Answer
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Correct Answer
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Correct Answer
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D

Correct Answer
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Correct Answer
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C

Correct Answer
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Correct Answer
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Correct Answer
verified

Describe the morphologic appearance of the red cells given the following results. RBC: 1.89*10¹²/L Hemoglobin: 7.5 g/dL Hematocrit: 21.0% RDW: 18.5

Correct Answer
verified

Correct Answer
verified

Correct Answer
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