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Exam 19: Anemias: Red Blood Cell Morphology and Approach to Diagnosis

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Question 1

Multiple Choice

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What is the best definition of anemia?

A) red cell count 10% lower than the patient's baseline
B) decreased hemoglobin, hematocrit, and red cell count compared with healthy people in the same demographic group
C) hemoglobin below 12 g/dL
D) any clinical condition resulting in shortness of breath, increased heart rate, pallor, and fatigue

E) B) and C)
F) B) and D)

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Question 2

Multiple Choice

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Which of the following is true of ineffective erythropoiesis?

A) Lymphopenia and anemia are present.
B) RBC production in bone marrow is increased.
C) Release of RBCs to the peripheral blood is normal.
D) RBC survival in circulation is less than 40 days.

E) None of the above
F) C) and D)

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B

Question 3

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Which of the following is typically a macrocytic anemia?

Which of the following conditions would warrant a bone marrow aspiration?

Match the letter of the correct composition for the inclusion with the number for the inclusion. Correct identification of inclusions in RBCs, when present, provides useful clinical information. They often help suggest the possible cause of an anemia and thus further appropriate testing. The first list provides some red cell inclusions. The second list provides choices for composition. -Heinz body

Which of the following disorders would be consistent with the previously mentioned parameters?

Describe the morphologic appearance of the red cells given the following results. RBC: 1.89 × 10¹²/L Hemoglobin: 7.5 g/dL Hematocrit: 21.0% RDW: 18.5

Which of the following is an example of a morphologic classification of anemia?

The reticulocyte response in patients with moderate anemia is often misinterpreted as adequate if:

Two different patients both have hemoglobins in the 5.0 to 6.0 g/dL range.One has pallor,fatigue,and headaches,whereas the other is experiencing life-threatening shock.Which of the following is probably the major difference between the two patients?

Match the letter of the correct composition for the inclusion with the number for the inclusion. Correct identification of inclusions in RBCs, when present, provides useful clinical information. They often help suggest the possible cause of an anemia and thus further appropriate testing. The first list provides some red cell inclusions. The second list provides choices for composition. -Howell-Jolly body

Match the letter of the correct composition for the inclusion with the number for the inclusion. Correct identification of inclusions in RBCs, when present, provides useful clinical information. They often help suggest the possible cause of an anemia and thus further appropriate testing. The first list provides some red cell inclusions. The second list provides choices for composition. -Basophilic stippling

The anemia found in liver disease is

Which of the following red blood cell (RBC) findings is specific for a certain condition as opposed to being nonspecific and found in many conditions?

What is the approximate average life span of a normal RBC in circulation?

Match the letter of the correct composition for the inclusion with the number for the inclusion. Correct identification of inclusions in RBCs, when present, provides useful clinical information. They often help suggest the possible cause of an anemia and thus further appropriate testing. The first list provides some red cell inclusions. The second list provides choices for composition. -Pappenheimer body

An appropriately increased RPI greater than 3 is associated with

Which of the following is a microcytic anemia?

All of the following are physiologic adaptations the body makes when a slow drop in the number of red cells occurs except

What test is used along with the mean cell volume (MCV) to morphologically classify anemias?